The Combination of Soursop and Turmeric Leaf Extracts Improves Lipid Profiles in Metabolic Syndrome Model Mice

Soursop and turmeric leaves have been studied to contain secondary metabolites such as flavonoids, saponins, tannins, sitosterol, curcumin, which the potential prevent metabolic syndrome. The aim of this study was determine ability a combination soursop leaf extract improve lipid profile levels in syndrome rat models total cholesterol (KT,) LDL, Tligserida (TG), HDL, VLDL. This experimental research design used post-test only control group method. A 36 rats were randomly divided into 6 groups, normal (N); syndrome(SM); SM+atorvastatin 0.18 mg/200 gBB (SMA); SM+combination 150:50 mg/kgBB(K1); 100:100 mg/kgBB(K2); 50:150 mg/kgBB(K3). mean KT, TG, LDL VLDL K2 groups significantly lower than SM (p-value<0,05). Compared HDL K2, higher So, improved model with best dose mg/kgBB.